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[Multiple myeloma. An unusual case].

F Silva1, M Z Veiga, J Viegas

  • 1Serviço 2 Medicina, Hospital de Curry Cabral, Lisboa.

Acta Medica Portuguesa
|April 1, 1992
PubMed
Summary
This summary is machine-generated.

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This case study highlights a rare presentation of multiple myeloma (MM) in an elderly male with paraplegia. Despite normal initial blood tests, further investigation confirmed MM with unusual laboratory findings.

Area of Science:

  • Oncology
  • Hematology
  • Neurology

Background:

  • Multiple myeloma (MM) is a plasma cell malignancy.
  • Typical MM diagnosis involves detecting monoclonal proteins in serum or urine.

Observation:

  • A 75-year-old male presented with sudden paraplegia and vertebral lesions.
  • Initial laboratory tests, including serum immunoglobulins, were unremarkable.

Findings:

  • Diagnosis of MM was confirmed via immunoelectrophoresis and necropsy.
  • The patient exhibited monoclonal gammopathy IgG, kappa light chain type, with low serum IgG and high urinary Bence Jones proteins.

Implications:

  • This case suggests a potential heavy chain suppression of the malignant clone.

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  • The atypical laboratory findings underscore the importance of comprehensive diagnostic approaches in suspected MM.