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Evaluation of ultrasound for assessing facial lipoatrophy in a randomized, placebo-controlled trial
Dianne Carey1, Handan Wand, Allison Martin
1National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, Australia.
Abstract:
We investigated the utility of ultrasonography for assessing facial lipoatrophy changes in HIV-infected adults receiving antiretroviral therapy who participated in a 48-week, randomized, placebo-controlled trial of rosiglitazone. Ultrasound was performed at weeks 0, 24 and 48 to determine the subcutaneous fat thickness over the malar bone. Changes in facial fat assessed by ultrasonography did not correlate significantly with more established objective measures of lipoatrophy severity. The measurement of malar fat using ultrasonography is not recommended.
