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Updated: Aug 16, 2026

Investigating Functional Regeneration in Organotypic Spinal Cord Co-cultures Grown on Multi-electrode Arrays
Published on: September 23, 2015
Fractal analysis of the laminar organization of spinal cord neurons
Nebojsa T Milosević1, D Ristanović, J B Stanković
1Institute of Biophysics, Medical School, University of Belgrade, Visegradska 26, 11000 Belgrade, Serbia and Montenegro. mtn@infosky.net
Abstract:
Images of Golgi impregnated neurons from different laminae of the human and rat dorsal horns were subjected to a quantitative analysis to support the Rexed's laminar scheme in mammals. Four methods of fractal analysis were performed in the proceedings: box-counting, mass-radius, cumulative intersection, and vectorized intersection. The results show that the box-counting method is more precise than the other fractal methods performed, and offers support for the conclusion that fractal analysis can successfully discriminate the neuron populations among different laminae. The analysis supports the concept of Rexed's cytoarchitectonic lamination of the dorsal horn.
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