Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Case reports: fibrosarcoma metastatic to the sciatic nerve.

R Lor Randall1, Andrew Dailey, Karen H Albritton

  • 1Sarcoma Services, Huntsman Cancer Institute and Primary Children's Medical Center, Salt Lake City, UT 84132, USA. R.Lor.Randall@hsc.uta.edu

Clinical Orthopaedics and Related Research
|August 2, 2005
PubMed
Summary

This study reports the first documented case of fibrosarcoma metastasizing to a major peripheral nerve, specifically the sciatic nerve. This rare cancer spread highlights a previously unknown metastatic pathway.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outcome of metastatic non-rhabdomyosarcoma soft tissue sarcoma in children and young adults treated on children's oncology group ARST0332 trial.

Journal of the National Cancer Institute·2026
Same author

A modified Delphi consensus on periprosthetic infection in orthopaedic oncology : a report from the Birmingham Orthopaedic Oncology Meeting (BOOM).

The bone & joint journal·2025
Same author

Factors Associated With Primary Site Local Therapy in Patients With Nonmetastatic Ewing Sarcoma Treated With Interval-Compressed Chemotherapy: A Report From the Children's Oncology Group.

International journal of radiation oncology, biology, physics·2025
Same author

What is debridement, antibiotics, and implant retention in orthopaedic oncology? : a global cross-sectional survey of surgeons' practices and opinions.

Bone & joint open·2025
Same author

A Phase 2 Trial of RANKL Antibody, Denosumab, in Two Cohorts of Patients with Recurrent/Refractory Osteosarcoma, a Report from the Children's Oncology Group.

Clinical cancer research : an official journal of the American Association for Cancer Research·2025
Same author

CORR Insights®: Genetic Variants Related to TGF-β Signaling Pathway Modulate Risk of Meniscus Injury: A Multiancestry Genome-wide Association Study.

Clinical orthopaedics and related research·2025

Area of Science:

  • Oncology
  • Neurology
  • Pathology

Background:

  • Fibrosarcoma is a rare malignant tumor originating from fibrous connective tissue.
  • Metastasis of fibrosarcoma to the central nervous system is known.
  • Spread to major peripheral nerves has not been previously documented.

Observation:

  • A unique case of fibrosarcoma with metastatic involvement of the sciatic nerve is presented.
  • This represents a novel site of metastasis for fibrosarcoma.

Findings:

  • The study confirms fibrosarcoma can metastasize to peripheral nerves.
  • The sciatic nerve was identified as a site of metastatic fibrosarcoma.

Implications:

  • This finding expands the understanding of fibrosarcoma metastatic patterns.

Related Experiment Videos

  • It suggests the need for broader diagnostic considerations in cases of sciatic nerve tumors.
  • Further research into the mechanisms of peripheral nerve metastasis is warranted.