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Identification of a ROB-1 beta-lactamase in Haemophilus ducreyi
I W Maclean1, L Slaney, J M Juteau
1Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada.
Antimicrobial Agents and Chemotherapy
|February 1, 1992
Abstract:
A collection of 100 clinical isolates of Haemophilus ducreyi from Thailand were all found to harbor a 5.4-kb plasmid, designated pTH126, which was shown to contain the bla ROB-1 gene. Restriction enzyme analysis and DNA-DNA hybridization studies confirmed that pTH126 was similar to the ROB-1 beta-lactamase plasmid pVM105 from Actinobacillus pleuropneumoniae. In approximately one-half of the isolates, pTH126 was found together with pHD131, which mediates TEM-1 beta-lactamase production.