HRT and the cardiovascular system

Oestrogen is cardioprotective for women. Not only does it have a beneficial effect on the circulating blood lipid fractions, but it is now established that oestrogen has a positive influence in preventing the deposit of cholesterol in the arterial endothelium. It also induces vasodilation, increases peripheral blood flow and leads to a fall in blood pressure. The use of oestrogen to reduce cardiovascular disease far outweighs any potential adverse changes.