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[Chromosomal translocation (2;13) in disseminated rhabdomyosarcoma]
P Pérez-Vera1, G Braun, R Rivera-Luna
1Departamento de Investigación en Genética Humana, Instituto Nacional de Pediatría, México, D.F.
Boletin Medico Del Hospital Infantil De Mexico
|May 1, 1992
Abstract:
A 12-year-old male with a disseminated alveolar rhabdomyosarcoma is reported. The diagnosis was difficult because of the clinical manifestations and the histological patterns of the bone marrow and a chest wall tumor. Diagnosis was confirmed through the histologic picture of a gum biopsy and the karyotype of the tumoral cells of the bone marrow. Chromosome study revealed a hypotetraploid cell line with the translocation (2;13) characteristic of this type of neoplasias. The usefulness of chromosome studies in solid tumors of childhood is emphasized.