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Manipulation of Epileptiform Electrocorticograms (ECoGs) and Sleep in Rats and Mice by Acupuncture
Published on: December 22, 2016
Sleep deprivation and epilepsy
1Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee 37212, USA. beth.malow@vanderbilt.edu
Abstract:
This review summarizes the data for and against sleep deprivation as a facilitator of epileptic seizures and interictal epileptiform discharges. Much of these data are derived from clinical studies; however, basic science investigations are greatly needed to determine the influence of sleep deprivation on seizure susceptibility and neuronal function. Study of the effects of sleep deprivation on epilepsy may create a window of opportunity that could help decipher how seizures are triggered and facilitated, potentially providing an avenue for future interventions.
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