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Updated: Aug 16, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
Live three-dimensional transthoracic echocardiographic assessment of ventricular noncompaction
Kunal Bodiwala1, Andrew P Miller, Navin C Nanda
1Division of Cardiovascular Diseases, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Insights
Three-dimensional transthoracic echocardiography (3D TTE) aids in diagnosing left ventricular noncompaction, especially when two-dimensional TTE is inconclusive. This advanced imaging reveals detailed myocardial structures for accurate assessment.
Area of Science:
- Cardiology
- Medical Imaging
Background:
- Left ventricular noncompaction is a rare congenital heart defect.
- Accurate diagnosis is crucial for patient management and prognosis.
Purpose of the Study:
- To evaluate the utility of live three-dimensional transthoracic echocardiography (3D TTE) in diagnosing noncompaction.
- To compare 3D TTE findings with two-dimensional TTE (2D TTE) in patients with noncompaction.
Main Methods:
- Case series of eight adult patients with noncompaction.
- Utilized live 3D TTE to visualize myocardial trabeculations and intertrabecular recesses.
- Compared 3D TTE findings with prior 2D TTE diagnoses.
Main Results:
- 3D TTE revealed prominent trabeculations, deep recesses, and a honeycombing appearance in all eight patients.
- Extensive right ventricular trabeculations were noted in combined left and right ventricular noncompaction cases.
- 3D TTE enabled diagnosis in five patients initially missed by 2D TTE.
Conclusions:
- Live 3D TTE is a valuable tool for diagnosing noncompaction, particularly when 2D TTE is insufficient.
- 3D TTE provides superior visualization of myocardial architecture compared to 2D TTE.
- This technique can improve diagnostic accuracy for noncompaction.
Abstract:
We present eight adult patients with noncompaction (four with isolated left ventricular noncompaction and four with combined left and right ventricular noncompaction) in whom live three-dimensional transthoracic echocardiography (3D TTE) demonstrated multiple, prominent myocardial trabeculations, deep intertrabecular recesses communicating with the ventricular cavity, and a typical honeycombing appearance. In the four patients with combined right and left ventricular noncompaction, very extensive trabeculations in the right ventricle were identified, much more than in normal or hypertrophied right ventricles. Five of the eight patients were not definitively identified to have noncompaction on two-dimensional (2D) TTE, but the diagnosis was made with 3D TTE. These cases demonstrate the potential usefulness of 3D TTE as a supplement to 2D TTE in the assessment of noncompaction.
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