Related Experiment Video
Updated: Aug 16, 2026

An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps
Published on: December 5, 2025
DIEP-flap failure after pedicle division three years following transfer
S E Moolenburgh1, M A van Huizum, S O P Hofer
1Department of Plastic, Reconstructive and Hand Surgery, Erasmus University Medical Centre Rotterdam, P.O. Box 2040, NL-3000 CA Rotterdam, The Netherlands.
Abstract:
Flap neovascularisation is generally believed to make free skin-containing flaps independent of their axial pedicle blood supply. A case of DIEP-flap failure 3 years after transfer is presented in a breast reconstruction patient in whom a lateral breast reduction for symmetry improvement was performed. Causative factors in this patient were the division of the flap pedicle during lateral breast reduction and smoking in the postoperative period. A review of literature is presented and highlights the uniqueness of this case.

