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Lentigo maligna. Cytogenetic, ultrastructural, and phenotypic characterization of a primary cell culture
P Grammatico1, A Modesti, K Steindl
1Dipartimento di Medicina Sperimentale, Università degli Studi di Roma La Sapienza, Italy.
Cancer Genetics and Cytogenetics
|June 1, 1992
Abstract:
Lentigo maligna is an early cutaneous neoplastic lesion. This article presents the cytogenetic, ultrastructural, and phenotypic characterization of a primary cell culture obtained from a patient affected with lentigo maligna. Two cellular clones were identified, both characterized by chromosomal markers involving chromosome 10 with a breakpoint at 10q26.