Related Experiment Video
Updated: Aug 16, 2026

Using Caenorhabditis elegans for Studying Trans- and Multi-Generational Effects of Toxicants
Published on: July 29, 2019
[Vilon effect on consequences of repeated radioactive and mercuric impact in small doses]
Abstract:
The purpose of the study was to determine the efficacy of vilon administration in rats after reiterated exposure to ecotoxicants (mercury in concentration near to maximum allowable one and gamma-radiation in small dose). In 24 hours after repeated radioactive and mercuric impact (RMI) and for 30 consecutive days the animals reported lymphopenia. At the same time the indices of DNA leucocytes content and structure did not differ from the parameters of intact animals, this could evidence the development of adaptation reactions. Vilon administration led to the normalization of the lymphocytes number by the 30th day after repeated irradiation (contrary to the radioactive- chemical control), while the number of granulocytes in the test group was higher than that in the intact control group. Study of the survival rate in rats revealed that Vilon reduced morbidity of rats in the course of 15 months after RMI.
Related Concept Videos
Biological Effects of Radiation
Toxicity Testing in Animals
Isotopes and Radioisotopes
An isotope containing more...
Dose Response Curve: Conventional Versus Nonmonotonic
Nuclear Transmutation
Radioactive Decay and Radiometric Dating
