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Preparation Of Gushukang (GSK) Granules for In Vivo and In Vitro Experiments
Published on: May 9, 2019
[The effect of preparation method on the quality of shen-mai injection]
Yong-jiang Wu1, Qin-min Cui, Yi-yu Cheng
1Department of Chinese Medicine Science and Engineering, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310027, China.
Objective:
To investigate the effect of different preparation method on the quality of Shen-mai injection.
Method:
The Shen-mai injection samples were prepared using three different methods. Fingerprints of Shen-mai extracts red ginseng, and its intermediates were obtained using an HPLC analytical procedure. The contents of ginsenoside Rg1, Rc and Rb1, and the gross saponins of Shen-mai extract were quantitatively mensured with HPLC procedures.
Result:
There was significant difference in fingerprints and chemical contents of the injections prepared by the three different methods.
Conclusion:
The quality of Shen-mai injection was greatly influenced by the preparation method. HPLC fingerprinting method can be applied for the determination of the Shen-mai preparations.