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Identifying DNA Mutations in Purified Hematopoietic Stem/Progenitor Cells
11:06

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DNA repair gene polymorphisms affect cytotoxicity in the National Cancer Institute Human Tumour Cell Line Screening

D B Yarosh1, A Peña, D A Brown

  • 1AGI Dermatics, Freeport, NY 11520, USA. danyarosh@agiderm.com

Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
|August 4, 2005
PubMed
Summary

Genetic variations in DNA repair genes influence cancer drug sensitivity. Certain polymorphisms, like XRCC1 R399Q, significantly increase sensitivity, highlighting DNA repair

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