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Arteries of the Head and Neck

Arteries of the Head and Neck

The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...

Veins of Head and Neck

Veins of Head and Neck

The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...

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Updated: Jan 8, 2026

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma

Published on: April 20, 2018

Head and neck angiosarcomas.

Bryan C McIntosh¹, Deepak Narayan

¹Hospital of St. Raphael, New Haven, Connecticut 06528, USA.

The Journal of Craniofacial Surgery

|August 4, 2005

Summary

This summary is machine-generated.

Head and neck angiosarcoma is a rare cancer with high mortality. Combined surgery and radiotherapy improved patient survival rates, offering a better prognosis for this aggressive neoplasm.

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Area of Science:

Oncology
Epidemiology
Medical Research

Background:

Angiosarcoma of the head and neck is a rare and aggressive malignancy.
Understanding the epidemiology and outcomes of this rare cancer is crucial for improving patient care.

Observation:

Analysis of the Connecticut Tumor Registry (1980-2001) identified head and neck angiosarcoma cases.
The study presents the first reported instance of familial head and neck angiosarcoma.
High mortality rates were observed: 48% at 1 year and 72% at 5 years.

Findings:

One-year mortality was 48% (38% males, 69% females).
Five-year survival was 28% (38% males, 15% females).
Combined surgery and radiotherapy demonstrated improved survival compared to single-modality treatment.

Implications:

Aggressive treatment strategies combining surgery and radiotherapy are recommended for head and neck angiosarcoma.
Further research into familial predispositions may elucidate genetic factors.
Improved understanding of risk factors and treatment efficacy is needed for this lethal neoplasm.