Related Experiment Video
Updated: Aug 16, 2026

Modeling Spontaneous Metastatic Renal Cell Carcinoma (mRCC) in Mice Following Nephrectomy
Published on: April 29, 2014
[Incidental renal cell carcinoma]
Yolanda Ares Valdés1, Ramiro Fragas Valdés
1Servicio de Urología, Hospital Universitario Manuel Fajardo, Ciudad de la Habana, Cuba. ares@infomed.sld.cu
Objectives:
To report the incidence and management of incidental renal cell carcinoma (RCC).
Methods:
We performed a retrospective longitudinal and panel study for our case series between January 1990 and December 2003. Thirty cases of RCC were analyzed, 6 of which were incidental.
Results:
4 patients were males (66.6%) and 2 females (33.3%); age ranged between 28 and 72 years. Reason for consultation was related with gastrointestinal symptoms. Ultrasound and CT scan are the most useful studies. Clinical stage was 4 T1 (66.6%), 2 T2 (33.3%). 4 radical nephrectomies and 2 conservative surgeries (partial nephrectomy and tumorectomy) were performed. A dose of 3 million units of alpha 2b recombinant interferon (IFN alpha 2b r) was given Intramuscularly two times a week over 6 months. Follow-up ranged between 120 and 60 months and none of the patients had evidence of tumor activity.
Conclusions:
The incidence of incidental RCC in our hospital is 20%. Clinical stage was always low and survival is directly related to stage. Conservative surgery showed similar survival than radical surgery.
Related Concept Videos
Acute Kidney Injury I: Introduction
Acute Kidney Injury II: Pathophysiology
Acute Kidney Injury IV: Diagnostic Studies and Prevention
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
Acute Kidney Injury III: Clinical Manifestations
Kidney Transplant II: Surgical Procedure
