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Updated: Aug 16, 2026

An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses
Published on: November 28, 2010
Primary angiosarcoma of the ovary: a case report of Stage I disease
Cherie D Quesenberry1, Cuizhen Li, Annette H Chen
1Department of Obstetrics and Gynecology, University of Massachusetts Memorial Hospital, 119 Belmont Street, Worcester, MA 01605, USA. quesenbc@ummhc.org
Background:
There are 20 documented cases of primary ovarian angiosarcoma. Most patients present with metastatic disease and respond poorly to chemotherapy. There is little information available to counsel early-staged patients on the need for or efficacy of adjuvant chemotherapy.
Case:
We present a case of Stage Ic primary ovarian angiosarcoma treated with 3 cycles of adjuvant MAID chemotherapy. The patient is without evidence of disease 10 months post-operatively.
Conclusion:
A review of the literature indicates a potential role for MAID chemotherapy in the treatment of ovarian angiosarcomas. Detection of Stage I disease appears to confer a better prognosis regardless of the utilization of adjuvant chemotherapy.
