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[The pathogen spectrum and its resistance behavior in children with urinary tract infections in Angola]

W Eggert1, S Eggert, E Ferreira

  • 1Klinik und Poliklinik für Kinderheilkunde, Medizinischen Fakultät Humboldt-Universität zu Berlin.

Kinderarztliche Praxis
|April 1, 1992
PubMed

Insights

This study analyzed bacterial infections in 225 children with urinary tract infections (UTIs). E. coli was the most common pathogen, showing high resistance to common antibiotics like trimethoprim/sulfamethoxazole.

Area of Science:

  • Pediatric infectious diseases
  • Microbiology
  • Pharmacology

Context:

  • Urinary tract infections (UTIs) are common in children.
  • Evaluating antibiotic resistance is crucial for effective treatment.

Purpose:

  • To determine the bacterial spectrum of UTIs in children.
  • To assess the antibiotic resistance patterns of common UTI pathogens.

Summary:

  • A study of 225 children with UTIs identified significant bacteriuria in 65.4%.
  • Escherichia coli was the most prevalent pathogen (34.6%), followed by Proteus (22.3%) and Klebsiella (14.6%).
  • High bacterial resistance was observed for trimethoprim/sulfamethoxazole, ampicillin, and gentamicin, while nitrofurantoin and nalidixic acid showed good susceptibility.

Impact:

  • Informs clinical decisions for pediatric UTI management.
  • Highlights the need for updated antibiotic susceptibility testing.
  • Guides the selection of effective antimicrobial agents for children with UTIs.

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