Related Experiment Video
Updated: Aug 16, 2026
Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
Evaluation of efficacy of an automated single-voxel proton MRS algorithm on a 3T system
Masaki Ohkubo1, Teruo Kimura, Hitoshi Matsuzawa
1Department of Radiological Technology, School of Health Sciences, Faculty of Medicine, University of Niigata, 2-746 Asahimachi-dohri, Niigata-shi, Niigata 951-8518, Japan. mook@clg.niigata-u.ac.jp
Purpose:
To evaluate the efficacy of a fully automatic, single-voxel, proton MR spectroscopy algorithm on a 3.0T MR system.
Methods:
The PROBE/SVQ algorithm (GE Medical Systems) was evaluated on a General Electric (GE) Signa LX-3T system. Ten normal volunteers (female, 21.1+/-2.0 years old) participated in the study. Nine representative regions of interest were examined, namely, right and left frontal white matter; right and left parietal white matter; right and left basal ganglia; right and left dentate nucleus; and pons.
Results:
The mean coefficients of variation in all regions for the N-acetyl-aspartate to creatine ratio (NAA/Cr), choline to creatine ratio (Cho/Cr), and choline to N-acetyl-aspartate ratio (Cho/NAA) were 10.2+/-2.4%, 11.4+/-3.2% and 12.6+/-1.4%, respectively.
Conclusion:
A fully automated spectroscopic examination under clinical setting utilizing the PROBE/SVQ algorithm appears to be a reliable method, extending the window of routine clinical assessment of brain metabolism.
More Related Videos
13:56The Use of Magnetic Resonance Spectroscopy as a Tool for the Measurement of Bi-hemispheric Transcranial Electric Stimulation Effects on Primary Motor Cortex Metabolism
Published on: November 19, 2014
10:06High-resolution Functional Magnetic Resonance Imaging Methods for Human Midbrain
Published on: May 10, 2012