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Updated: Aug 16, 2026

Rapid Generation of Amyloid from Native Proteins In vitro
Published on: December 5, 2013
Primary amyloidosis (AL) as a cause of nephrotic syndrome
Y Bataille1, C Bovy, P Lancellotti
1Department of nephrology and hypertension, University Hospital Liège, Domaine universitaire du Sart Tilman- B.35, B 4000 Liege 1, Belgique.
Abstract:
AL amyloidosis is a rare systemic disease resulting from tissue accumulation of amyloid fibrils derived from monoclonal immunoglobulin light chains. It can disrupt the tissue architecture and consequently cause organ dysfunction. The prognosis is poor with a median survival of 13 months in untreated patients. By illustrating the case of a patient whose AL amyloidosis was detected after presenting a nephrotic syndrome, the characteristics of the disease are reviewed as well as diagnostic criteria and current available therapeutics.
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