Related Experiment Video
Updated: Aug 16, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
Published on: May 17, 2024
Intra-operative diagnosis in surgical neuropathology: a study of 120 cases with reference to squash cytology
Shanop Shuangshoti1, Somruetai Shuangshoti, Samruay Shuangshoti
1Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand. trcssh@md.chula.ac.th
Objective:
To present results of intra-operative consultation in surgical neuropathology and discuss the diagnostic guideline for squash cytology.
Material And Method:
The intra-operative pathological diagnosis of 120 neurosurgical specimens was compared with the final histologic diagnosis. Squash preparation was used solely in 83 cases, frozen sections alone in 3 cases, and both techniques in the remaining. An algorithm for cytologic diagnosis was described.
Results:
The intra-operative pathological diagnoses in neurosurgery were completely (83%) and partially (13%) correlated with the final results.
Conclusions:
Intra-operative diagnosis in surgical neuropathology is reliable. Squash cytology is highly recommended as an alternative approach.

