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[Vitamin D status in Gabonese children]
B Nguema-Asseko1, P S Ganga-Zandzou, F Ovono
1Laboratoire de biochimie de la faculté de médecine de Libreville, Gabon.
Summary
Vitamin D supplementation is not necessary for infants aged 0-6 months in Gabon. Studies show no significant differences in health or vitamin D levels with or without supplements.
Area of Science:
- Pediatrics
- Nutritional Science
- Public Health
Background:
- Vitamin D is crucial for infant health, particularly bone development.
- The equatorial region of Gabon presents unique environmental factors potentially affecting vitamin D levels.
Purpose of the Study:
- To assess vitamin D status in neonates and infants up to 6 months in Gabon.
- To evaluate the efficacy of vitamin D supplementation in this population.
Main Methods:
- A comparative study involving two groups of infants (0-6 months).
- Group 1 received 1000 IU of vitamin D daily; Group 2 received no supplement.
- Clinical and biological parameters, including 25-hydroxyvitamin D levels, were monitored.
Main Results:
- No significant clinical differences were found between supplemented and unsupplemented groups.
- Biological parameters, including calcemia and phosphatemia, showed no significant variations.
- Plasma 25-hydroxyvitamin D levels were normal and similar in both groups.
Conclusions:
- Vitamin D supplementation appears unnecessary for infants aged 0-6 months in Gabon.
- Infants in this region may achieve adequate vitamin D levels through other sources.
- Further research could explore specific environmental or dietary factors contributing to sufficient vitamin D levels.
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Role of Skin in Vitamin D Synthesis
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
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Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
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Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
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Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...

