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Thyroid cancer in pregnancy
S Yasmeen1, R Cress, P S Romano
1Department of Obstetrics and Gynecology, University of California Davis, USA. syasmeen@ucdavis.edu
Summary
Thyroid cancer in pregnant women is diagnosed at similar stages and has no impact on survival. Treatment during pregnancy is safe for both mother and baby, indicating a good prognosis.
Area of Science:
- Oncology
- Maternal-Fetal Medicine
- Epidemiology
Background:
- Thyroid cancer diagnosis during pregnancy is rare.
- Understanding the impact of pregnancy on thyroid cancer prognosis is crucial for clinical management.
Purpose of the Study:
- To compare thyroid cancer stage at diagnosis, treatment, and survival in pregnant versus non-pregnant women.
- To evaluate the impact of thyroid cancer treatment on maternal and perinatal outcomes.
Main Methods:
- Utilized a database linking maternal/newborn discharge records with the California Cancer Registry (1991-1999).
- Compared pregnant women with thyroid cancer to age-matched non-pregnant controls.
Main Results:
- Identified 595 thyroid cancer cases (129 antepartum, 466 postpartum).
- Diagnoses occurred at Stage 2 in 64% of pregnant women vs. 58% of non-pregnant women.
- Pregnancy did not significantly affect mortality; thyroidectomy during pregnancy showed no adverse maternal/neonatal outcomes.
Conclusions:
- Thyroid cancer diagnosed during or after pregnancy does not significantly alter the disease prognosis.
- Treatment, including thyroidectomy, during pregnancy is safe for maternal and fetal well-being.
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