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Related Experiment Videos

Active infectious endocarditis: postoperative outcome.

Pascal Rosamel1, Maria Cervantes, Anne Tristan

  • 1Department of Anesthesia and Intensive Care, Hôpital Cardiovasculaire et Pneumologique Louis Pradel, BP Lyon Montchat, 69394 Lyon Cedex 03, France.

Journal of Cardiothoracic and Vascular Anesthesia
|August 9, 2005
PubMed
Summary

Active infectious endocarditis (AIE) requiring surgery is a severe condition. Outcomes depend on patient factors, not bacterial type, highlighting the need for comprehensive care.

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Area of Science:

  • Cardiology
  • Infectious Diseases
  • Cardiac Surgery

Background:

  • Active infectious endocarditis (AIE) management has evolved.
  • Tertiary care centers manage complex AIE cases.
  • Duke criteria are used for diagnosis.

Purpose of the Study:

  • To review outcomes of patients with AIE treated surgically.
  • To identify factors associated with hospital mortality in AIE patients.

Main Methods:

  • Retrospective review of 164 adult AIE patients over 3 years.
  • Exclusion of patients with pacemaker-related AIE.
  • Bacteriologic analysis including PCR and univariate regression for mortality factors.

Main Results:

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  • 60% of patients (98/164) underwent valvular surgery.
  • Commonly affected valves: aortic (72) and mitral (41).
  • Mortality (19 patients) linked to hemodynamic instability, age, comorbidities, and surgical factors; bacterial type was not significant.

    • Conclusions:

    • Active infectious endocarditis requiring cardiac surgery is a severe, resource-intensive disease.
    • Patient-specific factors, not pathogen, significantly impact outcomes.
    • Long-term sequelae, including neurological deficits, are a concern.