Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sublobar resection for the subcentimeter pulmonary nodule.

Ara Ketchedjian1, Benedict Daly, Rodney Landreneau

  • 1Department of Cardiothoracic Surgery, Boston Medical Center, Boston University, Boston, Massachusetts 02118, USA.

Seminars in Thoracic and Cardiovascular Surgery
|August 10, 2005
PubMed
Summary

Sublobar resection (SR) may be appropriate for select non-small-cell lung cancer (NSCLC) patients, challenging lobectomy as the sole standard. Careful nodal assessment is crucial for this less invasive approach in early-stage lung cancer.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Initial outcomes with uniportal video-assisted lung resection.

Interdisciplinary cardiovascular and thoracic surgery·2025
Same author

Corrigendum to: Lobectomy, segmentectomy, or wedge resection for peripheral clinical T1aN0 non-small cell lung cancer: A post hoc analysis of CALGB 140503 (Alliance)" [The Journal of Thoracic and Cardiovascular Surgery Volume 167, Issue 1, January 2024, Pages 338-347.e1].

The Journal of thoracic and cardiovascular surgery·2024
Same author

Recurrence of Non-Small Cell Lung Cancer With Visceral Pleural Invasion: A Secondary Analysis of a Randomized Clinical Trial.

JAMA oncology·2024
Same author

Robot-Assisted Bronchoscopy for Identification of Lung Nodules During Minimally Invasive Pulmonary Resection.

Innovations (Philadelphia, Pa.)·2024
Same author

Secondary Analysis of the Rate of Second Primary Lung Cancer From Cancer and Leukemia Group B 140503 (Alliance) Trial of Lobar Versus Sublobar Resection for T1aN0 Non-Small-Cell Lung Cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2024
Same author

Lobectomy, segmentectomy, or wedge resection for peripheral clinical T1aN0 non-small cell lung cancer: A post hoc analysis of CALGB 140503 (Alliance).

The Journal of thoracic and cardiovascular surgery·2023

Area of Science:

  • Thoracic Surgery
  • Surgical Oncology
  • Pulmonology

Background:

  • Lobectomy is the standard treatment for non-small-cell lung cancer (NSCLC).
  • Sublobar resection (SR) has historically shown higher recurrence rates than lobectomy.
  • Increased detection of small NSCLC tumors prompts reevaluation of surgical standards.

Purpose of the Study:

  • To review current literature on the use of sublobar resection (SR) as an intentional therapy for NSCLC.
  • To evaluate the evidence supporting SR for specific subsets of NSCLC patients.
  • To discuss the evolving role of SR in the context of early-stage lung cancer detection.

Main Methods:

  • Literature review of recent studies on sublobar resection (SR) for non-small-cell lung cancer (NSCLC).

Related Experiment Videos

  • Analysis of evidence regarding the efficacy and safety of SR compared to lobectomy.
  • Examination of factors influencing the decision-making process for SR in NSCLC treatment.

    • Main Results:

    • Lobectomy remains the preferred treatment for NSCLC due to lower recurrence rates.
    • SR is increasingly considered for small, peripheral NSCLC, especially in high-risk patients.
    • Evidence suggests SR may be appropriate for a carefully selected group of NSCLC patients with favorable characteristics.

    Conclusions:

    • While lobectomy is the gold standard for NSCLC, SR is a viable option for a subset of patients.
    • Careful assessment of nodal status is essential when considering SR for NSCLC.
    • Further research is needed to precisely define the criteria for appropriate intentional SR in NSCLC treatment.