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Reduced amplitude of the sural nerve sensory action potential in PARK2 patients
Y Ohsawa1, K Kurokawa, M Sonoo
1Division of Neurology, Department of Internal Medicine, Kawasaki Medical School, Kurashiki-City, Okayama 701-0192, Japan.
Abstract:
The authors performed nerve conduction studies in nine PARK2 and eight idiopathic Parkinson disease patients and found a significant reduction of sural sensory nerve action potential (SNAP) amplitude in eight PARK2 patients who mostly remained asymptomatic. These data suggest that sensory axonal neuropathy may be a common clinical feature of PARK2 and a reduced amplitude of sural SNAP could be a diagnostic indicator of PARK2.

