Related Experiment Video
Updated: Aug 16, 2026

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms
Published on: September 16, 2022
Effectiveness of antiinfectives
Ramona McLoughlin1, Colm O'Morain
1Adelaide and Meath Hospital, and Trinity College, Dublin, Ireland.
Background:
Helicobacter pylori is one of the most common infections of mankind, with persistent colonization causing significant morbidity and mortality.
Treatment:
First-line therapy, consisting of 7-day treatment with a proton pump inhibitor or ranitidine bismuth citrate, amoxicillin and clarithromycin, with second-line therapy, consisting of a proton pump inhibitor, bismuth, metronidazole, and tetracycline, in the case of failure, is chosen as the most cost-effective method of H. pylori eradication.
Conclusion:
The effectiveness of these antiinfectives is limited by lack of compliance with treatment regimens, and increasing antibiotic resistance.
Related Concept Videos
Antimicrobial Effectiveness
Combined Effects of Drugs: Synergism
Such synergistic combinations...
Surface Membrane Barriers
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
Hand hygiene
Hand washing...
Clinical Significance of Antibiotic Resistance
Dose-Response Relationship: Potency and Efficacy
