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Published on: February 18, 2012
Risk factors for preterm birth in Korea: a multicenter prospective study
Young Ju Kim1, Bo Eun Lee, Hye Sook Park
1Department of Obstetrics and Gynecology, Ewha Womans University, Seoul, Korea. kkyj@ewha.ac.kr
Gynecologic and Obstetric Investigation
|August 10, 2005
Summary
Preterm birth risk factors in Korean women include vaginal bleeding, low income, prior spontaneous abortion, and previous preterm delivery. Identifying these can help reduce neonatal morbidity and mortality.
Area of Science:
- Obstetrics and Gynecology
- Perinatal Medicine
- Reproductive Health
Background:
- Preterm birth significantly impacts neonatal health outcomes, posing a major challenge in obstetrics.
- Understanding specific risk factors is crucial for developing targeted prevention strategies.
Purpose of the Study:
- To investigate the key risk factors associated with preterm birth in a Korean population.
- To identify demographic, socioeconomic, and medical history factors influencing preterm delivery.
Main Methods:
- Prospective study involving 2,645 singleton pregnancies across 5 centers.
- Evaluation of demographic, socioeconomic, medical history, and lifestyle factors.
- Univariate and multivariate logistic regression analyses were performed.
Main Results:
- For nulliparous women, vaginal bleeding (OR 2.6) and income below USD 1,000 (OR 5.1) were significant risk factors.
- For multiparous women, a history of spontaneous abortion (OR 2.4) and prior preterm delivery (OR 3.5) were significant.
- These factors showed a positive association with preterm birth.
Conclusions:
- Vaginal bleeding during pregnancy is a significant risk factor for preterm birth in nulliparous women.
- Low socioeconomic status (income < USD 1,000) is associated with increased preterm birth risk.
- Previous pregnancy complications, including spontaneous abortion and preterm delivery, increase risk in multiparous women.
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