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Related Experiment Videos

Enterococcus: an emerging pathogen in hospitals.

Stephen G Weber1, Howard S Gold

  • 1Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.

Seminars in Respiratory and Critical Care Medicine
|August 10, 2005
PubMed
Summary
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Vancomycin-resistant enterococci (VRE) cause rising hospital infections, especially in the critically ill. Controlling VRE spread requires better infection control, but optimal strategies remain unclear.

Area of Science:

  • Infectious Diseases
  • Hospital Epidemiology
  • Antimicrobial Resistance

Background:

  • Enterococci are a significant cause of hospital-acquired infections, particularly in critically ill patients.
  • The incidence of enterococcal infections and infections caused by resistant strains is increasing nationwide.
  • Vancomycin-resistant enterococci (VRE) spread within hospitals through patient colonization and healthcare worker transmission.

Purpose of the Study:

  • To review the epidemiology and spread of VRE in healthcare settings.
  • To discuss infection control strategies for limiting VRE dissemination.
  • To highlight challenges in diagnosing and treating VRE infections, especially in critically ill patients.

Main Methods:

  • Review of existing literature on VRE epidemiology and control.

Related Experiment Videos

  • Analysis of VRE transmission dynamics in hospital environments.
  • Evaluation of current treatment options and emerging resistance patterns.

    • Main Results:

    • VRE colonization of hospitalized patients creates a reservoir for transmission.
    • Healthcare worker contact is a primary route for patient-to-patient VRE spread.
    • Limited prospective data exist on the efficacy of various infection control interventions.

    Conclusions:

    • Effective VRE control requires multifaceted infection prevention strategies, including hand hygiene and antibiotic stewardship.
    • Optimal strategies for limiting VRE dissemination are not yet established.
    • Treatment of VRE infections is challenging due to emerging resistance and drug toxicity, necessitating aggressive diagnosis and therapy in critically ill patients.