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Updated: Aug 4, 2026

Assessment of Right Ventricular Structure and Function in Mouse Model of Pulmonary Artery Constriction by Transthoracic Echocardiography
Published on: February 3, 2014
Assessment of right ventricular morphology and function
Mikhail Kosiborod1, Frans J Th Wackers
1Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520-8042, USA.
Assessing right ventricular function is crucial for pulmonary disease patients. Nuclear magnetic resonance imaging and radionuclide angiocardiography are preferred for accurate right ventricle morphology and function evaluation.
Area of Science:
- Cardiology
- Pulmonology
- Medical Imaging
Background:
- Right ventricular (RV) assessment is clinically important in pulmonary disease.
- RV's unusual geometry historically made evaluation difficult.
- Various diagnostic methods exist for RV assessment.
Purpose of the Study:
- To discuss diagnostic modalities for assessing RV morphology and function.
- To highlight the strengths and weaknesses of different imaging techniques.
Main Methods:
- Review of diagnostic modalities for RV assessment.
- Comparison of echocardiography, nuclear magnetic resonance imaging (NMRI), and radionuclide angiocardiography (RNGA).
Main Results:
- Echocardiography is widely available but may be limited.
- NMRI and RNGA are considered gold standards for RV assessment.
- NMRI and RNGA provide reliable and accurate measures of RV function and morphology.
Conclusions:
- Accurate assessment of RV morphology and function is vital in pulmonary disease.
- While echocardiography is common, NMRI and RNGA offer superior accuracy.
- NMRI and RNGA are the preferred methods for definitive RV evaluation.
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