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Long-term outcomes after ARDS.

C M Lee1, L D Hudson

  • 1Division of Pulmonary and Critical Care Medicine, Department of Medicine, Harborview Medical Center, University of Washington, School of Medicine, Seattle, Washington 98104, USA. cterrlee@u.washington.edu

Seminars in Respiratory and Critical Care Medicine
|August 10, 2005
PubMed
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Survivors of Acute Respiratory Distress Syndrome (ARDS) show unaffected long-term survival but experience significant respiratory, functional, and cognitive deficits. Recovery occurs over the first year, though some patients face persistent impairment and post-traumatic stress syndrome.

Area of Science:

  • Critical Care Medicine
  • Pulmonology
  • Rehabilitation Medicine

Background:

  • Early studies suggested minimal long-term sequelae for Acute Respiratory Distress Syndrome (ARDS) survivors.
  • Recent research with improved methodology offers a more nuanced understanding of life after ARDS.

Purpose of the Study:

  • To synthesize current evidence on the long-term outcomes of ARDS survivors.
  • To identify key areas of impact including survival, respiratory function, quality of life, and psychological well-being.

Main Methods:

  • Systematic review and synthesis of recent investigations on ARDS outcomes.
  • Contextualization of new findings with previously published literature.

Main Results:

Related Experiment Videos

  • Long-term survival is not impacted by ARDS itself but by risk factors and comorbidities.
  • Respiratory symptoms and pulmonary function improve within the first year, though some patients have persistent deficits.
  • Quality of life, functional independence, and cognitive function are significantly impaired initially but improve over time; ARDS survivors report lower quality of life than matched critically ill controls.
  • A notable percentage of ARDS survivors develop post-traumatic stress syndrome.

    • Conclusions:

    • ARDS survivors face significant, though often improving, long-term challenges beyond initial survival.
    • Further research is needed to validate findings, explore ramifications, and assess the impact of acute care interventions on long-term recovery.