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Related Experiment Videos

Nontuberculous mycobacteria in children: a changing pattern.

Thien-Tuong-Vi Vu1, Sam J Daniel, Caroline Quach

  • 1Division of Infectious Diseases, Department of Pediatrics and Medical Microbiology, Montreal Children's Hospital, McGill University Health Center, QC.

The Journal of Otolaryngology
|August 11, 2005
PubMed
Summary
This summary is machine-generated.

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Nontuberculous mycobacteria (NTM) adenitis cases have doubled, with more severe presentations in recent years. Complete surgical excision of affected lymph nodes offers the best resolution for this growing NTM disease.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Microbiology

Background:

  • Nontuberculous mycobacteria (NTM) infections are increasingly prevalent and severe globally.
  • NTM adenitis, a common manifestation, requires epidemiological and clinical assessment.

Purpose of the Study:

  • To document the epidemiology, clinical presentation, investigations, and treatment of NTM adenitis.
  • To assess the increase in NTM adenitis cases and severity over time at a major children's hospital.

Main Methods:

  • Retrospective chart review of patients diagnosed with NTM adenitis between 1990 and 2004.
  • Case identification through microbiology databases and medical records, including node biopsy or excision.

Main Results:

Related Experiment Videos

  • 36 NTM adenitis cases identified over 15 years, with 61% occurring in the last 5 years.
  • Majority presented with cervicofacial mass; 25% had constitutional symptoms. Invasive cases increased.
  • Complete surgical excision showed higher resolution rates compared to less invasive procedures.

    • Conclusions:

    • NTM adenitis cases nearly doubled from 2000-2004 compared to 1990-1999, with increased invasiveness.
    • Complete surgical excision is crucial for resolving NTM adenitis.
    • Further studies are needed to assess NTM disease incidence versus tuberculosis and PPD test recommendations.