[Pharmacosurveillance III: international experience]

This article, the third of the series called pharmacovigilance, deals with international experience with adverse drug reactions. It highlights the countries with the greatest cumulative number of reports and how their position changes with the use of the country-adjusted number of reports by million of inhabitants/year. It includes, in decreasing order, the number of reports of twenty therapeutic drug classes. Included in each one are the most plausible explanations for their frequency and, finally, the cumulative number of reports for clinical manifestations of adverse drug reactions.