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Comparison of Mantoux's test with diagnostic BCG in pediatric patients with pulmonary tuberculosis

Anis-ur-Rehman1, Muhammad Idris

  • 1Department of Paediatrics, Ayub Medical College, Abbottabad, Pakistan. midris63@yahoo.com

Journal of Ayub Medical College, Abbottabad : JAMC
|August 12, 2005
PubMed

Insights

In pediatric tuberculosis, the diagnostic BCG test shows higher positivity compared to the Mantoux test. This suggests BCG is more effective for diagnosing tuberculosis in children.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Immunology

Background:

  • Pulmonary tuberculosis (TB) is a significant health concern across all age groups.
  • Accurate diagnostic methods are crucial for effective TB management.
  • Pediatric TB diagnosis presents unique challenges.

Purpose of the Study:

  • To compare the diagnostic efficacy of the Mantoux test and the diagnostic BCG test.
  • To evaluate the performance of these tests in pediatric patients with confirmed pulmonary tuberculosis.

Main Methods:

  • A study involving 100 pediatric patients (up to 15 years) with pulmonary TB.
  • Simultaneous administration of Mantoux and diagnostic BCG tests to all participants.
  • Recording and comparison of patient responses to each test for positivity.

Main Results:

  • Both Mantoux and BCG tests yielded negative results in approximately 26% of cases.
  • Both tests were positive in about 40% of the pediatric TB patients.
  • The diagnostic BCG test alone was positive in 34% of cases where the Mantoux test was negative.

Conclusions:

  • The diagnostic BCG test demonstrates superior performance over the Mantoux test in diagnosing tuberculosis in the pediatric age group.
  • BCG testing offers a more sensitive diagnostic approach for pediatric TB.
Abstract

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