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Related Experiment Videos

A new method of continuous venovenous rewarming.

Jason M Hiles1, John P Schriver, Christopher D Wohltmann

  • 1Department of Surgery, William Beaumont Army Medical Center, El Paso, Texas, USA.

Current Surgery
|August 12, 2005
PubMed
Summary

Continuous venovenous rewarming (CVVR) with the FMS 2000 significantly speeds up rewarming in hypothermic pigs compared to external methods alone. This faster rewarming method also prevents dangerous core temperature drops.

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Area of Science:

  • Veterinary Medicine
  • Critical Care Medicine
  • Physiology

Background:

  • Hypothermia is a critical medical condition, often part of the 'deadly triad' with acidosis and coagulopathy.
  • Effective rewarming strategies are essential for managing moderate hypothermia.

Purpose of the Study:

  • To compare the efficacy of continuous venovenous rewarming (CVVR) using the FMS 2000 alongside external rewarming techniques versus external rewarming alone.
  • To evaluate rewarming effectiveness in a porcine model of moderate hypothermia.

Main Methods:

  • Ten pigs (approx. 40 kg) were randomly assigned to a control group (external rewarming only) or a CVVR group (FMS 2000 plus external rewarming).
  • Hypothermia was induced via cold water immersion to a core temperature of 30°C.
  • Core body temperatures were monitored every 15 minutes using esophageal and rectal probes until reaching at least 37°C.

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Main Results:

  • The CVVR group achieved rewarming in an average of 113 minutes, significantly faster than the control group's 253 minutes (p = 0.002 at 30 minutes).
  • A statistically significant difference in core temperature between groups was observed after 30 minutes of rewarming.
  • The control group experienced a significant core temperature after-drop, which was not observed in the CVVR group (p = 0.015 at 15 minutes).

Conclusions:

  • Continuous venovenous rewarming with the FMS 2000 is more effective than standard external rewarming alone for treating moderate hypothermia in a porcine model.
  • These findings suggest CVVR may be a valuable clinical tool for managing hypothermic patients.