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Updated: Aug 2, 2026
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Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
Published on: July 15, 2015
Renal transplantation in the elderly--the Irish experience
L Giblin1, M Hollander, D Little
1Irish Renal Transplant Registry, Department of Nephrology, Beaumont Hospital, Beaumont Road, Dublin 9.
Irish Journal of Medical Science
|August 13, 2005
Summary
Elderly kidney transplant recipients (≥65 years) showed comparable adjusted graft survival rates to younger patients, despite lower overall patient survival. Renal transplantation benefits both age groups.
Area of Science:
- Nephrology
- Transplantation Immunology
- Geriatric Medicine
Background:
- Renal transplantation is a critical treatment for end-stage renal disease.
- Assessing outcomes across different age demographics is crucial for optimizing transplant strategies.
Purpose of the Study:
- To evaluate and compare patient and kidney graft survival rates in renal transplant recipients.
- To analyze transplant outcomes stratified by patient age groups.
Main Methods:
- Retrospective review of adult renal transplants (1986-2001).
- Patients categorized as 'elderly' (≥65 years) or 'younger' (<65 years).
- Analysis of patient and graft survival rates for each age cohort.
Main Results:
- 1462 younger and 105 elderly recipients included.
- Younger patients had higher estimated patient survival at 1, 5, and 10 years (96%, 87%, 74%) vs. elderly (85%, 59%, 33%).
- Adjusted graft survival rates at 1, 5, and 10 years were similar: younger (89%, 77%, 64%) vs. elderly (89%, 83%, 70%).
Conclusions:
- Elderly renal transplant recipients experience shorter life expectancy.
- Despite this, elderly patients significantly benefit from renal transplantation.
- Outcomes suggest renal transplantation is a viable option for older adults, with comparable graft survival to younger recipients.
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