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Updated: Aug 16, 2026

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
Published on: February 6, 2020
Self-assembly, binding, and dynamic properties of heterodimeric porphyrin macrocycles
Pablo Ballester1, Antoni Costa, Pere M Deyà
1ICREA and Institute of Chemical Research of Catalonia (ICIQ), 43007-Tarragona, Spain. pballester@iciq.es
Abstract:
A series of heterodimeric tetralactam macrocycles have been self-assembled using two kinetically labile zinc porphyrin-pyridine interactions. The stability constants have been determined by UV-vis titrations in CHCl3. The stability constants depend on the degree of preorganization of the linker units connecting the interacting groups. The ability of the self-assembled macrocycles to bind a terephthalamide guest was also investigated. One of the macrocycles was used for the construction of a [2]rotaxane. The dynamic properties of this system provide insight into the exchange mechanisms that operate in complex noncovalent assemblies.
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