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Updated: Aug 12, 2026

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model
Published on: August 13, 2017
The bioexpandable prosthesis: a new perspective after resection of malignant bone tumors in children
Rainer Baumgart1, Stefan Hinterwimmer, Michael Krammer
1Klinikum der Universität München Chirurgische Klinik und Poliklinik-Innenstadt, Munich, Germany. Rainer.Baumgart@med.uni-muenchen.de
Abstract:
Bone reconstruction after resection of malignant bone tumors of the lower extremity in children and adolescents remains a challenge in limb-sparing surgery. Equal limb length at maturity and good functional outcome are the main goals of these surgeries but often are difficult to achieve. Expandable endoprostheses are available but usually require repeated operative interventions for lengthening. Moreover, as the size of the implant increases, the proportion of the implant relative to the remaining bone increases, generating a biomechanical disadvantage to the limb. The authors describe a new concept combining an endoprosthesis with a fully implantable motorized distraction nail that can be activated in gradual steps to lengthen the remaining bone by callus distraction. New high-quality bone is growing and the proportion of prosthesis length compared with leg length develops in favor of the remaining bone.

