Related Experiment Video

Updated: Aug 16, 2026

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
05:56

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Published on: April 3, 2016

Long-term visual prognosis of infantile-onset high myopia

Y-F Shih1, T-C Ho, C K Hsiao

  • 1Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan. yfshih@ha.mc.ntu.edu.tw

Eye (London, England)
|August 13, 2005
PubMed

Insights

Infantile high myopia progression varies by severity. Lower myopia levels tend to worsen, while higher levels may stabilize or regress, with most children achieving good vision.

Area of Science:

  • Ophthalmology
  • Pediatric Ophthalmology
  • Refractive Errors

Background:

  • Infantile-onset high myopia presents unique challenges in visual development and management.
  • Understanding the long-term clinical course is crucial for predicting visual outcomes in affected children.

Purpose of the Study:

  • To analyze the refractive status changes in children with infantile-onset high myopia treated with full correction.
  • To determine the visual prognosis and identify factors influencing myopia progression or regression.

Main Methods:

  • A cohort of 57 children with infantile-onset high myopia (>-5.0 D before age 5) received full correction.
  • Data collected included cycloplegic refraction, axial length, and best-corrected visual acuity every 6 months.
  • The mean follow-up duration was 9.36 years.

Main Results:

  • Myopia progression/regression correlated with initial refractive error severity.
  • Lower myopia (-5.0 to -7.75 D) showed higher progression rates compared to the highest myopia group (<= -11.0 D).
  • The highest myopia group exhibited greater regression rates; 80% achieved >20/40 vision, with 37% >20/25.

Conclusions:

  • Infantile high myopia follows a distinct clinical course compared to school-age myopia.
  • Higher initial myopia degrees often lead to stabilization or regression.
  • Lower degrees of infantile high myopia demonstrate a significant tendency for progression.
Abstract

More Related Videos

An Automated Method for Assessing Visual Acuity in Infants and Toddlers Using an Eye-Tracking System05:10

An Automated Method for Assessing Visual Acuity in Infants and Toddlers Using an Eye-Tracking System

Published on: March 17, 2023

Related Concept Videos

Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Focusing of Light in the Eye01:16

Focusing of Light in the Eye

Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Prosopagnosia01:24

Prosopagnosia

Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...