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[Double kidney transplantation].

Pierre Mongiat-Artus1

  • 1Service d'Urologie, Hôpital Saint-Louis, Paris, France. pierre.mongiat-artus@sls.ap-hop-paris.fr

Progres En Urologie : Journal De L'Association Francaise D'Urologie Et De La Societe Francaise D'Urologie
|August 16, 2005
PubMed
Summary
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Double kidney transplantation effectively utilizes "borderline" deceased donor kidneys for end-stage renal failure patients, showing satisfactory graft survival and function with low morbidity. Further research is needed to refine donor and recipient selection criteria for optimal outcomes.

Area of Science:

  • Nephrology and Transplant Surgery
  • Organ Transplantation Research
  • Public Health and Epidemiology

Context:

  • Increasing incidence of end-stage renal failure and rising mean age of kidney transplant candidates.
  • Significant shortage of available deceased donor kidneys for transplantation.
  • Exploration of "borderline" deceased donor kidneys as a potential solution to the organ shortage.

Purpose:

  • To review medical literature on double kidney transplantation experiences and outcomes.
  • To assess the efficacy, safety, and feasibility of utilizing "borderline" kidneys through double transplantation.
  • To identify areas for improvement in donor and recipient selection criteria for this procedure.

Summary:

  • Double kidney transplantation involves using two "borderline" deceased donor kidneys in one recipient, often older patients, to address organ shortages.

Related Experiment Videos

  • The procedure demonstrates satisfactory graft survival and function (serum creatinine ~200 µmol/l at 3 years) with low patient morbidity.
  • While overall recruitment of "borderline" kidneys increased by 10%, complications like ureteric strictures can occur, necessitating refined selection criteria.

    • Impact:

    • Successfully increases the utilization of "borderline" deceased donor kidneys, expanding transplant options for patients.
    • Provides a viable alternative for older transplant candidates, improving access to kidney transplantation.
    • Highlights the need for standardized donor and recipient selection protocols to optimize outcomes and resource allocation in kidney transplantation.