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Repair of left ventricular aneurysm during off-pump coronary artery bypass surgery
Yang Yu1, Cheng-xiong Gu, Hua Wei
1Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital University of Medical Science, Beijing 100029, China. dr_yuyang@sohu.com
Insights
This study shows that surgically closing left ventricular aneurysms during off-pump coronary artery bypass surgery is safe and effective. The procedure led to improved heart function and reduced symptoms in patients with post-infarction left ventricular aneurysms.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery
- Interventional Cardiology
Background:
- Left ventricular aneurysm (LVA) following acute myocardial infarction can lead to severe complications such as congestive heart failure and ventricular arrhythmias.
- Surgical intervention for LVA is often complex and associated with significant risks.
Purpose of the Study:
- To evaluate the outcomes of a modified linear closure technique for LVAs.
- To assess the safety and efficacy of performing this repair during off-pump coronary artery bypass (OPCAB) surgery.
Main Methods:
- A cohort of 75 patients with nonruptured LVAs underwent repair during OPCAB surgery between January 2001 and May 2004.
- Repair was performed on the beating heart to allow functional assessment and guide closure.
- Preoperative and postoperative cardiac performance, including ejection fraction and left ventricular end-diastolic diameter, were compared using statistical analysis.
Main Results:
- The study reported a low hospital mortality rate of 1.3%.
- Patients received an average of 3.3 coronary artery bypass grafts.
- Significant improvements were observed in mean NYHA class (P < 0.001), ejection fraction (P < 0.001), and a significant decrease in left ventricular end-diastolic diameter (P < 0.001).
Conclusions:
- Surgical closure of LVAs during OPCAB is a feasible and safe procedure.
- The technique is associated with low in-hospital mortality and morbidity.
- Early postoperative improvements in cardiac function, symptoms, and quality of life suggest potential for increased long-term survival.
Background:
Acute myocardial infarction can result in left ventricular aneurysm, which may in turn cause congestive heart failure, ventricular arrhythmia and thromboembolic events. This study evaluates results achieved with a modified linear closure of left ventricular aneurysms during off-pump coronary artery bypass surgery.
Methods:
From January 2001 to May 2004, 75 patients were operated on for nonruptured, postinfarctional, left ventricular aneurysm during off-pump coronary artery bypass surgery. Repair was completed on the beating heart to minimize ischaemia and allow assessment of wall function and viability to guide closure. All patients presented with symptoms of angina and congestive heart failure or ventricular arrhythmia. The majority (75%) of the patients were in NYHA functional class III or IV. Preoperative ejection fraction was 26% +/- 9%. The mean left ventricular, end diastolic diameter was (57.5 +/- 7.1) mm. The ventricular preoperative and postoperative performances were compared. chi2 test and Student's t test were used to analyse the outcomes. A P value less than 0.05 was considered significant.
Results:
Hospital mortality was 1.3% (1/75). Coronary artery bypass was performed with an average of (3.3 +/- 1.2) grafts per patient. At the time of followup, all the patients had no symptoms. The mean NYHA class and ejection fraction increased significantly (P < 0.001). The mean left ventricular, end diastolic diameter decreased significantly (P < 0.001).
Conclusions:
Surgical closure of left ventricular aneurysm can be performed during off-pump coronary artery bypass. The operation is associated with a low inhospital mortality and morbidity. A postoperative improvement in the early term cardiac functions and symptoms and quality of life was documented, increasing our expectations of an increased long-term survival.
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