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Molecularly targeted agents: their promise as cancer chemopreventive interventions
A Thiery-Vuillemin1, T Nguyen, X Pivot
1Department of Medicine, Institut Gustave Roussy, 39 Rue Camille Desmoulins, 94805 Villejuif, France.
Abstract:
Molecular medicine has fully entered in to the oncology arena. The development of targeted therapies is one of the major ongoing efforts in cancer treatment. Targeted therapy refers to treatment strategies directed against molecular targets considered to be involved in neoplastic transformation. Such molecularly targeted agents (MTA) are currently under study in all treatment settings including that of chemoprevention, defined as the use of natural or synthetic agents to interrupt the carcinogenic process, to nip tumours in the bud. This review article aims to provide a general overview of the potential use of some of these MTA in the chemoprevention setting.
Insights
Molecularly targeted agents (MTA) show promise in cancer prevention. This review explores the potential of MTA in chemoprevention to interrupt tumor development.
Area of Science:
- Oncology
- Molecular Medicine
Background:
- Molecular medicine is increasingly integrated into oncology.
- Targeted therapies are a key focus in cancer treatment development.
- Molecularly targeted agents (MTA) are designed to act on specific molecular targets involved in cancer.
Purpose of the Study:
- To provide an overview of MTA in cancer chemoprevention.
- To explore the potential of MTA to interrupt the carcinogenic process.
Main Methods:
- This is a review article.
- It synthesizes information on MTA for chemoprevention.
Main Results:
- MTA are being investigated for various cancer treatment settings.
- Their application in chemoprevention is a significant area of research.
Conclusions:
- MTA hold potential for cancer chemoprevention.
- Further research into MTA for interrupting tumor development is warranted.
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