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Updated: Aug 16, 2026

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
Published on: June 24, 2020
Previous maternal infection with Toxoplasma gondii and the risk of fetal death
Katherine T Chen1, Anne Eskild, Michaeline Bresnahan
1Department of Obstetrics and Gynecology, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA. ktc10@columbia.edu
Objective:
The purpose of this study was to assess the association between previous maternal Toxoplasma gondii (T gondii) infection and risk of fetal death.
Study Design:
This was a population-based prospective cohort of 29,912 pregnant women without acute T gondii infection in Norway.
Results:
In the study population, 2937 (9.8%) women had evidence of previous maternal T gondii infection, and 299 (1.0%) had fetal deaths. We found no association between previous T gondii infection and risk of fetal death at > or = 20 weeks of gestation. We did find a trend for an increased risk of fetal death at > or = 16 and <20 weeks of gestation. However, we noted no association between previous T gondii infection and risk of fetal death at all birth weight categories (> or = 1000, > or = 500 and <1000, and <500 g).
Conclusion:
These data do not indicate an increased risk of fetal death at > or = 20 weeks of gestation in women with previous maternal T gondii infection.
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