Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Embryonic Stem Cells00:57

Embryonic Stem Cells

3.8K
Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
3.8K
Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

5.2K
Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
5.2K
Stem Cell Culture01:17

Stem Cell Culture

5.5K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
5.5K
Adult Stem Cells01:33

Adult Stem Cells

30.7K
Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
30.7K
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.2K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.2K
Multipotency of Hematopoietic Stem Cells01:19

Multipotency of Hematopoietic Stem Cells

3.3K
The hematopoietic stem cells or HSCs are multipotent, meaning they can differentiate and give rise to all blood and immune cells. HSCs are maintained in the quiescent stage until an external stimulus initiates their differentiation. The multipotent HSCs exist as two heterogeneous populations, long-term repopulating cells (LTRC) and short-term repopulating cells (STRC). The two HSC populations have different surface markers or receptors and are classified based on quiescence and long-term...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Introducing a new proforma for the safe use of intraoperative tourniquets in orthopaedic surgery.

Annals of the Royal College of Surgeons of England·2024
Same author

Pre-operative resuscitation discussion with patients undergoing fractured neck of femur repair: a service evaluation and discussion of current standards.

Archives of orthopaedic and trauma surgery·2021
Same author

Laccase isoform diversity on basal medium in Cyathus bulleri and role in decolorization/detoxification of textile dyes and effluent.

World journal of microbiology & biotechnology·2020
Same author

Direct versus indirect transfer for traumatic brain injury to James Cook University Hospital: a retrospective study.

Annals of the Royal College of Surgeons of England·2020
Same author

Slipped capital femoral epiphysis: is it worth the risk and cost not to offer prophylactic fixation of the contralateral hip?

The bone & joint journal·2015
Same author

Controlling intrathoracic hemorrhage on ECMO: help from Factor VIIa and Virchow.

Perfusion·2012
Same journal

Assisted dying and the silencing of medicine's next generation.

Lancet (London, England)·2026
Same journal

Linguistic pragmatism: a woman with progressive abdominal pain in Thailand.

Lancet (London, England)·2026
Same journal

Medical compartmentalisation: a patient with chromosome 22q11.2 deletion syndrome in Japan.

Lancet (London, England)·2026
Same journal

[<sup>177</sup>Lu]Lu-edotreotide versus everolimus for gastroenteropancreatic neuroendocrine tumours (COMPETE): a phase 3, multicentre, randomised, open-label, superiority trial.

Lancet (London, England)·2026
Same journal

Research priorities for characterising Bundibugyo virus.

Lancet (London, England)·2026
Same journal

Rethinking treatment sequence in advanced gastroenteropancreatic neuroendocrine tumours.

Lancet (London, England)·2026
See all related articles

Related Experiment Video

Updated: Oct 1, 2025

Author Spotlight: Importance of Single Cell Sorting in Isolating Purified Populations of Mesenchymal Stem Cells
13:44

Author Spotlight: Importance of Single Cell Sorting in Isolating Purified Populations of Mesenchymal Stem Cells

Published on: November 10, 2023

2.1K

Stem cells.

A Vats1, R C Bielby, N S Tolley

  • 1Tissue Engineering and Regenerative Medicine Centre, Imperial College London, Chelsea and Westminster Campus, London, UK. a.vats@imperial.ac.uk

Lancet (London, England)
|August 16, 2005
PubMed
Summary
This summary is machine-generated.

Adult and embryonic stem cells offer therapeutic promise but require more research for widespread clinical use. Comparing their characteristics is crucial for determining the best source for regenerative medicine applications.

More Related Videos

Induced Pluripotent Stem Cell Generation from Blood Cells Using Sendai Virus and Centrifugation
09:57

Induced Pluripotent Stem Cell Generation from Blood Cells Using Sendai Virus and Centrifugation

Published on: December 21, 2016

14.6K
Isolating Stem Cells from Soft Musculoskeletal Tissues
07:49

Isolating Stem Cells from Soft Musculoskeletal Tissues

Published on: July 5, 2010

13.5K

Related Experiment Videos

Last Updated: Oct 1, 2025

Author Spotlight: Importance of Single Cell Sorting in Isolating Purified Populations of Mesenchymal Stem Cells
13:44

Author Spotlight: Importance of Single Cell Sorting in Isolating Purified Populations of Mesenchymal Stem Cells

Published on: November 10, 2023

2.1K
Induced Pluripotent Stem Cell Generation from Blood Cells Using Sendai Virus and Centrifugation
09:57

Induced Pluripotent Stem Cell Generation from Blood Cells Using Sendai Virus and Centrifugation

Published on: December 21, 2016

14.6K
Isolating Stem Cells from Soft Musculoskeletal Tissues
07:49

Isolating Stem Cells from Soft Musculoskeletal Tissues

Published on: July 5, 2010

13.5K

Area of Science:

  • Regenerative Medicine
  • Stem Cell Biology
  • Biomedical Research

Background:

  • Adult and embryonic stem cells hold significant therapeutic potential.
  • Extensive research is necessary before widespread clinical application.
  • A key debate exists regarding the suitability of adult stem cells versus embryonic stem cells.

Purpose of the Study:

  • To compare and contrast adult and embryonic stem cells.
  • To identify characteristics that can inform the debate on stem cell sources.
  • To provide rationalization for the clinical use of different stem cell types.

Main Methods:

  • Comparative analysis of adult and embryonic stem cell characteristics.
  • Evaluation of accessibility, frequency, abundance, and potency.
  • Assessment of ethical considerations and potential risks.

Main Results:

  • Accessibility varies; neural stem cells are difficult to obtain from living donors.
  • Adult stem cell properties like numbers and potency may decline with age or disease.
  • Ethical concerns surround embryonic stem cells, and therapeutic cloning is often misrepresented.

Conclusions:

  • Further research is needed to fully assess stem cell stability, pathogen transmission, and teratoma risk.
  • A comprehensive comparison of adult and embryonic stem cells is essential for clinical decision-making.
  • Addressing ethical issues and clarifying misconceptions is vital for advancing stem cell therapies.