Related Experiment Video
Updated: Aug 16, 2026
Microbiological Rapid On-Site Evaluation for Pulmonary Infectious Diseases
Published on: March 1, 2024
Impact of rapid on-site cytologic evaluation during transbronchial needle aspiration
Daniel Baram1, Ruel B Garcia, Paul S Richman
1Division of Pulmonary/Critical Care, Stony Brook University, T-17, 040 HSC, Stony Brook, NY 11794-8172, USA. dbaram@notes.cc.sunysb.edu
Study Objective:
To determine the extent to which rapid on-site cytologic evaluation (ROSE) of transbronchial needle aspiration (TBNA) samples can safely and cost-effectively reduce the need for additional biopsy during bronchoscopy.
Setting:
University Hospital in Long Island, NY.
Patient And Methods:
Forty-four bronchoscopies with TBNA, most of which utilized ROSE, were evaluated prospectively. The number and types of biopsies performed during each procedure were compared to a preprocedural algorithm to determine the impact of knowing ROSE results during the procedure. Bronchoscopies performed with and without ROSE were compared, as were bronchoscopies with diagnostic and nondiagnostic ROSE results. A cost analysis was performed comparing the Medicare reimbursement for ROSE to the savings of deferring multiple biopsies.
Results:
Thirty-two bronchoscopies were performed with ROSE; 12 were performed without ROSE. Fewer biopsies were performed during bronchoscopies utilizing ROSE. Diagnostic yield, TBNA sensitivity and accuracy, and procedural time were similar between these two groups.
Conclusions:
ROSE during TBNA allows for deferring additional biopsy without loss in diagnostic yield, likely lowers procedural risk, and is cost-effective.
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