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Updated: Aug 12, 2026

12:37
Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
[Decrease of mutagenic action of cyclophosphamide by buckwheat melanin preparation]
Ukrains'Kyi Biokhimichnyi Zhurnal (1999 )
|August 17, 2005
Abstract:
Melanins are polyphenolic pigments of plants, animals and microbes with antioxidant and antiradiation activity. Water-soluble melanin from buckwheat is experienced as antimutagenic means (0.01-10 mg/kg per os) for cyclophosphamide (20 mg/kg i.p.) in the 3 series of experiments. The frequency of chromosome aberrations in the cells of mice bone marrow after mutagene is reduced 2-6 times once under influence of melanin.

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