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Updated: Aug 5, 2026
16:13
Modeling Neural Immune Signaling of Episodic and Chronic Migraine Using Spreading Depression In Vitro
Published on: June 13, 2011
Depression in chronic migraine: severity and clinical features
Juliane Prieto Peres Mercante1, Mario Fernando Prieto Peres, Vera Guendler
1Psicóloga, pesquisadora do Instituto de Ensino e Pesquisa do Hospital Israelita Albert Einstein, São Paulo SP, Brasil. julianeperes@terra.com.br
Arquivos De Neuro-Psiquiatria
|August 17, 2005
Summary
Over 85% of chronic migraine patients experience depression, with over 58% having moderate to severe symptoms. This highlights the critical need for mental health screening in chronic migraine care.
Area of Science:
- Neurology
- Psychiatry
- Clinical Research
Background:
- Chronic migraine (CM) affects 2.4% of the population.
- Depression is a frequent comorbidity in CM patients.
Purpose of the Study:
- To assess the prevalence and severity of depression in patients with chronic migraine.
- To explore correlations between depression and other clinical factors in CM.
Main Methods:
- Seventy patients with diagnosed chronic migraine were evaluated.
- The Beck Depression Inventory (BDI) was used to assess depression severity.
- Depression levels were categorized as none/minimal, mild, moderate, or severe.
Main Results:
- 85.8% of patients reported some degree of depression.
- 58.7% experienced moderate or severe depression.
- Depression severity correlated with pain intensity (p=0.02) and was higher in patients with fibromyalgia and fatigue.
Conclusions:
- The Beck Depression Inventory is a practical tool for identifying depression in CM patients.
- Suicide risk assessment is crucial for CM patients.
- Fibromyalgia and fatigue increase the risk of severe depression in this population.
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