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Updated: Aug 16, 2026

Modeling Hepatitis B Virus Infection in Non-Hepatic 293T-NE-3NRs Cells
Published on: June 5, 2020
Hepatitis virus B is not a risk factor in hepatoblastoma patients
1Department of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand. wviroj@pioneer.netserv.chula.ac.th
Abstract:
The prevalence of primary liver cancer varies throughout the world. Hepatoblastoma is the most common pediatric liver malignancy, comprising approximately 1% of all pediatric cancers. The exact etiology of hepatoblastoma remains undetermined. Concerning hepatitis B infection, whether there are links with hepatoblastoma is poorly documented. Here, we summarize knowledge on the prevalence of hepatitis B seropositives among the patients with hepatoblastoma. According to the literature review, six reports were recruited for metanalysis, with a total of 60 cases. The overall prevalence of seropositive cancer was 3.3 % (2/560). Further analysis revealed no correlation between prevalence rate and nationality of the studied population (P > 0.05). Therefore, hepatitis B infection does not appear to be a contributing factor for hepatoblastoma. Further studies are needed to clarify which are the risk factors for the hepatoblastoma.
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