Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Protein misfolding and misprocessing in complex disease.

A Fadiel1, K D Eichenbaum, A Hamza

  • 1Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, School of Medicine, New Haven, CT 06520, USA. afadiel@yale.edu

Protein and Peptide Letters
|August 17, 2005
PubMed
Summary

Scientists explored protein misfolding and misprocessing in disease, highlighting its role in complex illnesses. Understanding these biochemical mechanisms is key to developing new therapeutic strategies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Chloral Hydrate versus Isofluorane anesthesia and their differential impact on the midbrain system.

Journal of neuroscience methods·2026
Same author

The impact of targeted therapies on molecular alterations identified by an institutional molecular tumor board: an approach based on ESCAT classification.

ESMO real world data and digital oncology·2026
Same author

Achievement of Target Gain Larger than Unity in an Inertial Fusion Experiment.

Physical review letters·2024
Same author

Stereocontrol via Propeller Chirality in FLP-Catalyzed Asymmetric Hydrogenation.

Chemistry (Weinheim an der Bergstrasse, Germany)·2024
Same author

Didymin protects against polystyrene nanoplastic-induced hepatic damage in male albino rats by modulation of Nrf-2/Keap-1 pathway.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas·2024
Same author

Accuracy of Whole Blood Cardiac Troponin I in the Diagnosis of Childhood Heart Failure at the University College Hospital, Ibadan.

West African journal of medicine·2023

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Pathology

Background:

  • Protein misfolding and misprocessing are implicated in the etiology of numerous complex diseases.
  • A comprehensive understanding of disease mechanisms requires analyzing associated biochemical pathways.

Framework:

  • Focus on protein folding patterns and processing.
  • Investigate the role of chaperone regulators in protein homeostasis.
  • Examine stress pathways and signal transduction mechanisms involved in disease pathogenesis.

Implementation:

  • Convened scientists from over 20 major research centers.
  • Discussed recent advances and novel discoveries in the field.
  • Synthesized current knowledge on protein misfolding and misprocessing.

Related Experiment Videos

Implications:

  • Advances in understanding protein mechanisms can elucidate complex disease etiology.
  • Identifying key biochemical pathways offers targets for therapeutic intervention.
  • Cross-institutional collaboration accelerates scientific discovery in protein-related diseases.