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Updated: Aug 16, 2026
Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System
Published on: December 7, 2012
Gamma irradiation does not affect 7-day storage of platelet concentrates
P F van der Meer1, R N I Pietersz
1Sanquin Blood Bank North West region, Amsterdam, the Netherlands. p.vandermeer@sanquin.nl
Background And Objectives:
Extension of storage of leucocyte-reduced platelet concentrates (LR-PCs) to 7 days has recently been introduced, but the effect of gamma irradiation on in vitro parameters was unknown.
Materials And Methods:
A paired experiment was carried out, with gamma irradiation on day 1 or day 5 with 25 Gy, and no irradiation served as a reference.
Results:
Measurements during storage up to 8 days after blood collection showed no significant differences of irradiated LR-PCs vs. the control.
Conclusions:
Irradiation, either on day 1 or day 5, had no effect on platelet quality during a 7-day storage period.
